Signal processing by the endosomal system

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Signal processing by the endosomal system.

Cells need to decode chemical or physical signals from their environment in order to make decisions on their fate. In the case of signalling receptors, ligand binding triggers a cascade of chemical reactions but also the internalization of the activated receptors in the endocytic pathway. Here, we highlight recent studies revealing a new role of the endosomal network in signal processing. The d...

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ژورنال

عنوان ژورنال: Current Opinion in Cell Biology

سال: 2016

ISSN: 0955-0674

DOI: 10.1016/j.ceb.2016.02.002